It’s the most wonderful time of the year. No, not Christmas.

It’s NCAA Tournament Time AKA March Madness. Like most of the country, there is a strong chance you’re filling out your bracket, which will promptly fall apart after the first four games (better to break your heart now). Maybe you’ve done your homework and can make a thorough case for South Dakota State over Gonzaga – you can’t – or maybe you’re crafting your bracket around your favorite shade of red or species of bird. Either way, nobody likes someone who picks straight favorites the whole bracket. Then again, if you know anything about bracket building, it’s that navigating the 5-12, 4-13, and 7-10 games can be the difference between bragging rights and busted brackets. So which of these matchups can separate your bracket from the rest?